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MDM2 抗体 (Ser166)

MDM2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN540533
发货至: 中国
  • 抗原 See all MDM2 抗体
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    抗原表位
    • 26
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    • 14
    • 11
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    Ser166
    适用
    • 194
    • 79
    • 54
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 169
    • 28
    • 1
    克隆类型
    • 169
    • 29
    多克隆
    标记
    • 99
    • 13
    • 9
    • 9
    • 7
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    • 6
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    • 2
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    • 2
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    • 2
    • 2
    • 2
    • 1
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    This MDM2 antibody is un-conjugated
    应用范围
    • 126
    • 77
    • 64
    • 37
    • 28
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    • 27
    • 18
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    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic peptide of MDM2.
    序列
    AISET
    特异性
    MDM2 (Ab-166) Antibody detects endogenous levels of total MDM2 protein.
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S166 of human MDM2.
    Top Product
    Discover our top product MDM2 Primary Antibody
  • 应用备注
    Immunohistochemistry (1:50-1:100)
    Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Mayo, Donner: "A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11598-603, (2001) (PubMed).

    Zhou, Liao, Xia, Zou, Spohn, Hung: "HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation." in: Nature cell biology, Vol. 3, Issue 11, pp. 973-82, (2001) (PubMed).

  • 抗原
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    别名
    MDM2 (MDM2 产品)
    别名
    ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
    基因ID
    4193
    途径
    p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
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