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ERBB3 抗体 (pTyr1328)

ERBB3 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN540462
发货至: 中国
  • 抗原 See all ERBB3 抗体
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    抗原表位
    • 28
    • 26
    • 21
    • 15
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    pTyr1328
    适用
    • 181
    • 127
    • 112
    • 17
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 187
    • 28
    • 1
    • 1
    克隆类型
    • 185
    • 32
    多克隆
    标记
    • 112
    • 13
    • 10
    • 10
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    • 10
    • 10
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    • 5
    • 5
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    • 4
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    • 1
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    This ERBB3 antibody is un-conjugated
    应用范围
    • 101
    • 67
    • 53
    • 53
    • 50
    • 31
    • 28
    • 20
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    • 8
    • 3
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of ERBB3.
    序列
    PDYpWH
    特异性
    Her3/ErbB3 (phospho-Tyr1328) Antibody detects endogenous levels of Her3/ErbB3 only when phosphorylated at tyrosine 1328.
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1328 of human ERBB3.
    Top Product
    Discover our top product ERBB3 Primary Antibody
  • 应用备注
    Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:100)
    Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Kobayashi, Iwamatsu, Shinohara-Kanda, Ihara, Fukui: "Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas." in: Oncogene, Vol. 22, Issue 9, pp. 1294-301, (2003) (PubMed).

    Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: "The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8933-8, (2003) (PubMed).

    Yarden, Sliwkowski: "Untangling the ErbB signalling network." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 2, pp. 127-37, (2001) (PubMed).

  • 抗原
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    别名
    ERBB3 / HER3 (ERBB3 产品)
    别名
    ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
    基因ID
    2065
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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