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MAPK8IP1 抗体 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1)

Details for Product anti-MAPK8IP1 Antibody No. ABIN4904305, 供应商: Log in to see
抗原
  • IB1
  • JIP-1
  • Jip1
  • Prkm8ip
  • Skip
  • mjip-2a
  • JIP1
  • Jip-1
  • Mapk8ip
  • PRKM8IP
  • mitogen-activated protein kinase 8 interacting protein 1
  • MAPK8IP1
  • LOC100344706
  • Mapk8ip1
适用
人, 小鼠
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宿主

69
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1
克隆类型
多克隆
标记
This MAPK8IP1 antibody is un-conjugated
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应用范围
Western Blotting (WB)
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Supplier
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Supplier Product No.
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Available images

免疫原 Recombinant protein of human MAPK8IP1.
亚型 IgG
产品特性 This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.
纯化方法 Affinity purification
别名 MAPK8IP1 (MAPK8IP1 Antibody 摘要)
基因ID 9479
UniProt Q9UQF2
应用备注 WB 1:200-1:2000
限制 仅限研究用
状态 Liquid
浓度 1 mg/mL
缓冲液 PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze/thaw cycles.
储存条件 -20 °C
储存方法 Store at -20°C.
厂商提供的图像
Western Blotting (WB) image for anti-MAPK8IP1 抗体 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1) (ABIN4904305) Western blot analysis of extract of various cells, using MAPK8IP1 antibody.