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SEC23A 抗体 (Internal Region)

SEC23A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN488037
发货至: 中国
  • 抗原 See all SEC23A 抗体
    SEC23A (Sec23 Homolog A (SEC23A))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠, Cow, 犬, 马
    宿主
    • 24
    • 1
    山羊
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    This SEC23A antibody is un-conjugated
    应用范围
    • 19
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    Recognizes SEC23A.
    交叉反应 (详细)
    Species reactivity (expected):Human, Rat, Equine (Horse), Canine (Dog) and Bovine.
    Species reactivity (tested):Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence C-ANRAATTGHVID, from the internal region of the protein sequence according to NP_006355.2. Genename: SEC23A
    Top Product
    Discover our top product SEC23A Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit Dilution: 1/32000. Western blot: 1-3 μg/mL. Approx 100 kDa band observed in lysates of NIH3T3 (calculatedMW of 86.0 kDa according to Human NP_006355.2 and to Mouse NP_033173.2 ).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    SEC23A (Sec23 Homolog A (SEC23A))
    别名
    SEC23A (SEC23A 产品)
    别名
    Msec23 antibody, Sec23r antibody, wu:fc10f08 antibody, wu:fi15g03 antibody, zgc:55534 antibody, clsd antibody, DKFZp459O136 antibody, sec23a antibody, SEC23A antibody, CLSD antibody, SEC23 homolog A, COPII coat complex component antibody, Sec23 homolog A, coat complex II component antibody, Sec23 homolog A, COPII coat complex component antibody, protein transport protein Sec23A antibody, Sec23 homolog A, COPII coat complex component S homeolog antibody, COP-II coat subunit antibody, Sec23 homolog B, coat complex II component antibody, Sec23a antibody, sec23a antibody, SEC23A antibody, LOC576977 antibody, sec23a.S antibody, LOC100183335 antibody, SEC23B antibody
    背景
    The regulation of intracellular vesicular trafficking is mediated by specific families of proteins that are involved in vesicular budding, translocation, and fusion with target membranes. The protein trafficking between endoplasmic reticulum (ER) and Golgi apparatus is mediated by two distinct membrane coat complexes, COPI and COPII. Two Coat protein II (COPII) proteins are necessary to generate secretory vesicles at the endoplasmic reticulum. COPI consist of 7 protein subunits includinga, b, b1, d, e, d, z. COPI is also responsible for the retrograde golgi to ER transport f dilysine-tagged proteins. Sec23A is a functional human counter part of the yeast COPII component Sec23p which suggests that it plays similar role in the mammalian protein export from ER. Both Sec 23 isoforms (Sec23A and Sec23B) have similar molecular weight 85 kDa and are co-expressed in many human tissues at varying levels of expression. In yeast, the Sec24p protein is the only COPII component in which two close orthologues have been identified. Sec-23p is a component of coat protein II (COPII) coated vesicles involved in protein export from the endoplasmic reticulum (Mizoguchi et. al., 2000). The COPII is required for the vesicle budding from the endoplasmic reticulum and is consist of two heterodimeric subcomplexes, Sec23p/Sec24p and Sec13p/Sec31p and a small GTPase Ser1p (Higashio et al., 2000). Recent data also suggest that Sec23p/Sec24p complexes are in addition to its role in the shaping up of the vesicle, the Sec23-24p complex may be implicated in cargo selection and trafficking of the amount of cargo with in the cells.Synonyms: Protein transport protein Sec23A, SEC23-related protein A
    基因ID
    10484
    NCBI登录号
    NP_006355
    UniProt
    Q15436
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