Peptide ELISA: 1/4000. Immunofluorescence: This product has been successfully used by an anonymous customeron methanol-fixed and 0.5 % TX100-permeabilized HeLa cells, staning thecytoplasm. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Mad3 antibody, BHLHC13 antibody, MAD3 antibody, MYX antibody, 4631412E13Rik antibody, bHLHc13 antibody, Mad antibody, zgc:66281 antibody, Myx antibody, MAX dimerization protein 3 antibody, Max dimerization protein 3 antibody, MAX dimerization protein 3 L homeolog antibody, mxd3 antibody, MXD3 antibody, Mxd3 antibody, mxd3.L antibody
背景
MAD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.Synonyms: MAD-3, MXD3, Max-interacting transcriptional repressor MAD3