EYA1
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 680
应用备注
Peptide ELISA: 1/16000. Western blot: Approx 55 kDa band observed in lysates of cell lline HEK293 (calculated MWof 60.5 kDa according to NP_742056.1). Recommended concentration: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
0.5 mg/mL
缓冲液
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
EYA1 (Eyes Absent Homolog 1) is a member of the eyes absent (EYA) family of proteins. EYA1 plays a role in transcriptional regulation during organogenesis. It is thought play a role in the development of the kidney, branchial arches, eye and ear. EYA1 is thought to coactivate SIX2, SIX4 and SIX5. EYA1 has intrinsic protein phosphatase activity, and dephosphorylates proteins such as Histone H2.AX phosphorylated on Y142. It is thought to play a role in promoting efficient DNA repair over apoptosis in response to genotypic stress.Synonyms: Eyes absent homolog 1