PCSK1 抗体 (Middle Region)
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- 抗原 See all PCSK1 抗体
- PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
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抗原表位
- Middle Region
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适用
- 大鼠, 人, 小鼠, 豚鼠, 马, 兔, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCSK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- QSPKKSPSAK LNIPYENFYE ALEKLNKPSQ LKDSEDSLYN DYVDVFYNTK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against PCSK1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PCSK1
- Top Product
- Discover our top product PCSK1 Primary Antibody
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anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 500-738) antibody
PCSK1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 244-530) antibodyPCSK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 652-753) antibodyPCSK1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 652-754) antibodyPCSK1 适用: 大鼠, 人, 小鼠 WB, IHC (p), IF, EIA 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 682-715) antibodyPCSK1 适用: 大鼠, 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB55298 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 683-732) antibodyPCSK1 适用: 人, 豚鼠, 马, Cow, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 652-753) antibodyPCSK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 175-207) antibodyPCSK1 适用: 大鼠 WB 宿主: 兔 Polyclonal RB55297 unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 726-740), (C-Term) antibodyPCSK1 适用: 大鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (Middle Region) antibodyPCSK1 适用: 大鼠, 人, 小鼠, 豚鼠, 马, 兔, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 753 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
- 别名
- PCSK1 (PCSK1 产品)
- 别名
- BMIQ12 antibody, NEC1 antibody, PC1 antibody, PC3 antibody, SPC3 antibody, Nec-1 antibody, Nec1 antibody, Phpp-1 antibody, BDP antibody, PC1/3 antibody, proprotein convertase subtilisin/kexin type 1 antibody, prohormone convertase 1 antibody, PCSK1 antibody, Pcsk1 antibody, pcsk1 antibody, PC1B antibody
- 背景
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PCSK1 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NEC1, PC1, PC3, SPC3, BMIQ12
Protein Interaction Partner: env, AFF1, PCSK1N, REN, PMCH, IAPP, PTK2, CTNNB1,
Protein Size: 753 - 分子量
- 71 kDa
- 基因ID
- 5122
- NCBI登录号
- NM_000439, NP_000430
- UniProt
- P29120
- 途径
- Peptide Hormone Metabolism
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