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RING1 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects RING1 in WB 和 IHC. It exhibits reactivity toward 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN487036
发货至: 中国
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Quick Overview for RING1 抗体 (Middle Region) (ABIN487036)

抗原

See all RING1 抗体
RING1 (Ring Finger Protein 1 (RING1))

适用

  • 67
  • 20
  • 19
  • 7
  • 6
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

  • 50
  • 20

克隆类型

  • 39
  • 31
多克隆

标记

  • 42
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RING1 antibody is un-conjugated

应用范围

  • 54
  • 20
  • 17
  • 15
  • 14
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    APSPPEPGGE IELVFRPHPL LVEKGEYCQT RYVKTTGNAT VDHLSKYLAL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against RING1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RING1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 406 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RING1 (Ring Finger Protein 1 (RING1))

    别名

    RING1

    背景

    RING1 belongs to the RING finger family, members of which characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The protein can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. RING1 interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. This gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: RNF1, RING1A
    Protein Interaction Partner: CBX8, RYBP, YAF2, BMI1, UBC, SNAI1, EED, RNF2, HECW2, CSNK2A2, YY1, FBXO38, CBX7, CBX6, FHL1, TP53, NOTCH1, APP, PCGF1, PCGF5, PCGF6, PCGF3, PCGF2, CBX2, PHC3, WDR5, CBX4, PHC2, PHC1, YY2, ZFP42, SMARCAD1, PIK3R3, TOP2A, TERF2, TERF1, USP11, USP7, CENPA,
    Protein Size: 406

    分子量

    42 kDa

    基因ID

    6015

    NCBI登录号

    NM_002931, NP_002922

    UniProt

    Q06587
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