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- 抗原 See all ELF3 抗体
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
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抗原表位
- Middle Region
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适用
- 人, Cow, 犬, 兔, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GSCGAGAPSP GSSDVSTAGT GASRSSHSSD SGGSDVDLDP TDGKLFPSDG
- 预测反应
- Cow: 86%, Dog: 79%, Horse: 92%, Human: 100%, Pig: 93%, Rabbit: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ELF3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human Elf3
- Top Product
- Discover our top product ELF3 Primary Antibody
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anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 1-280) antibody
ELF3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 1-280) antibodyELF3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 262-371) antibodyELF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (C-Term) antibodyELF3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (N-Term) antibodyELF3 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) antibodyELF3 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (AA 147-371) antibodyELF3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (C-Term) antibodyVerified ELF3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) (N-Term) antibodyELF3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) antibodyELF3 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 371 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
- 别名
- Elf3 (ELF3 产品)
- 别名
- ert antibody, esx antibody, epr-1 antibody, ese-1 antibody, ESE-1 antibody, ESX antibody, jen antibody, EPR-1 antibody, ERT antibody, E74 like ETS transcription factor 3 antibody, E74-like factor 3 antibody, elf3 antibody, Elf3 antibody, ELF3 antibody
- 背景
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ELF3 is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family. ELF3 contains two putative DNA binding domains: an ETS domain, which is unique in that the 5' half shows relatively weak homology to known ets factors, and an A/T hook domain, found in HMG proteins and various other nuclear factors. In contrast to any known ets factors, ELF3 is expressed exclusively in epithelial cells. ELF3 is expected to be a critical regulator of epithelial cell differentiation. ETS factor ELF3 is a transcriptional regulator of angiopoietin-1 gene regulation in the setting of inflammation. ELF3 overexpressed early during human breast tumorigenesis. ELF3 expression confers a transformed and in vitro metastatic phenotype to otherwise normal MCF-12A cells. ELF3 mediates the expression of TGF-beta RII, and the transcriptional inhibition of ets-related transcription factor could be a one of the mechanisms of colonic carcinogenesis. ELF3 is positively and negatively modulated by other interacting proteins including Ku70, Ku86, p300, and CBP.
Alias Symbols: EPR-1, ERT, ESE-1, ESX
Protein Interaction Partner: MED23, XRCC5, RPL6, XRCC6, EP300, CBR3, Jun, MYC, BTRC, UBC, PAK1, TAF9, SUMO2, TBP, EPS15, CREBBP, NFKB1, EGFR, ERBB2, EHF, GANAB, ISG15, TARS, P4HB, KRT82, KRT31, JAK1, EEF1D, DDX3X, CALR, ATIC,
Protein Size: 371 - 分子量
- 41 kDa
- 基因ID
- 1999
- NCBI登录号
- NM_004433, NP_004424
- UniProt
- P78545
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