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PDHX 抗体

PDHX 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357415
发货至: 中国
  • 抗原 See all PDHX 抗体
    PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))
    适用
    • 23
    • 20
    • 17
    人, 小鼠
    宿主
    • 35
    • 3
    • 1
    • 1
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDHX antibody is un-conjugated
    应用范围
    • 31
    • 13
    • 13
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PDX1.
    纯化方法
    Protein A column, followed by peptide affinity purification
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T11 of human PDX1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDHX Primary Antibody
  • 应用备注
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))
    别名
    PDHX / PDX1 (PDHX 产品)
    别名
    DLDBP antibody, E3BP antibody, OPDX antibody, PDX1 antibody, proX antibody, AI481367 antibody, E3bp antibody, Pdx1 antibody, Ac1164 antibody, zgc:66110 antibody, zgc:85977 antibody, MGC86218 antibody, PDHX antibody, DDBDRAFT_0168431 antibody, DDBDRAFT_0230192 antibody, DDB_0168431 antibody, DDB_0230192 antibody, pyruvate dehydrogenase complex component X antibody, pyruvate dehydrogenase complex, component X antibody, pyruvate dehydrogenase complex component X L homeolog antibody, E3-binding protein antibody, PDHX antibody, Pdhx antibody, pdhx antibody, pdhx.L antibody, pdhX antibody
    背景
    PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.Synonyms: Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein, E3BP, Lipoyl-containing pyruvate dehydrogenase complex component X, Pyruvate dehydrogenase protein X component mitochondrial, proX
    分子量
    54122 Da predicted from amino acid sequence. Theoretical pI: 8.80.
    基因ID
    8050, 9606
    UniProt
    O00330
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