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beta Amyloid 抗体

Abeta 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal OMAB unconjugated
产品编号 ABIN459388
发货至: 中国
  • 抗原 See all beta Amyloid (Abeta) 抗体
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    适用
    • 69
    • 22
    • 15
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 41
    • 26
    • 3
    • 2
    小鼠
    克隆类型
    • 37
    • 29
    • 1
    单克隆
    标记
    • 62
    • 5
    • 2
    • 1
    • 1
    • 1
    This beta Amyloid antibody is un-conjugated
    应用范围
    • 53
    • 49
    • 28
    • 17
    • 15
    • 13
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应 (详细)
    Not reactive in: no confirmed exceptions from predicted reactivity known in the moment
    预测反应
    rat
    产品特性
    Expected / apparent Molecular Weight of the Antigene: 4.5 kDa
    OMAB antibody is a versatile tool within research of Alzheimer’s disease. A sandwhich ELISA illustrates its potential regarding its high selectivity towards Aβ oligomers. OMAB antibody has been purified by by ion-exchange chromatography.
    纯化方法
    affinity purified
    免疫原
    partly aggregated, recombinant peptide corresponding to the human Abeta (1-40/42). Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V. The epitope is 3-8.
    克隆位点
    OMAB
    亚型
    IgM
    Top Product
    Discover our top product Abeta Primary Antibody
  • 应用备注
    coating antibody at 2 μg/mL (ELISA), 1: 500 (IHC)
    说明

    OMAB antibody is a versatile tool within research of Alzheimer's disease. A sandwhich ELISA illustrates its potential regarding its high selectivity towards Aβ oligomers.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    For reconstitution add 100 μL of sterile water.
    缓冲液
    PBS without any additives as carrier proteins or sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
    储存条件
    4 °C
    储存方法
    store lyophilized/reconstituted at 4°C. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
  • 抗原
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    别名
    Amyloid beta oligomer-specific (Abeta 产品)
    别名
    AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, aaa antibody, abeta antibody, abpp antibody, ad1 antibody, appi antibody, ctfgamma antibody, cvap antibody, pn2 antibody, Abeta antibody, Abpp antibody, Adap antibody, Ag antibody, Cvap antibody, E030013M08Rik antibody, betaApp antibody, amyloid beta precursor protein antibody, amyloid beta (A4) precursor protein antibody, APP antibody, app antibody, App antibody
    背景
    Soluble oligomeric assemblies of the Amyloid-β peptide are today anticipated to be the direct cause regarding the Alzheimer pathology. As a consequence, oligomeric Aβ-assemblies constitute a very interesting therapeutic target. Identification of Aβ-oligomers is however, technically challenging due to there labile nature and low abundance. Abeta oligomer-specific OMAB antibody is based on the IgM isotype and represents a new concept of Aβ-oligomer binders using a combination of high avidity and very low monovalent affinity. This combination creates a selectivity of the antibody towards the oligomeric fraction and minimizes reactivity towards monomeric species.
    分子量
    4.5 kDa
    途径
    Inflammasome
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