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小鼠 anti-人 IgM (Fc Region) Antibody (HRP)

ABIN457359 产品详细信息, 供应商: Log in to see
抗原
抗原表位
Fc Region
558
373
290
63
56
51
46
28
6
6
2
1
1
1
1
适用

1190
559
232
92
80
67
66
58
56
56
56
40
35
28
19
15
15
7
5
5
2
1
1
1
宿主
小鼠
1262
664
511
143
38
11
10
9
4
3
3
2
克隆类型 (克隆位点)
单克隆 ()
标记
HRP
356
343
271
157
99
74
67
53
25
25
23
22
22
19
18
16
16
16
16
15
14
14
13
12
9
7
7
5
5
5
4
4
4
4
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
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免疫原 Purified human IgM.
克隆位点 CH2
亚型 IgG1
特异性 The antibody CH2 reacts with Fc fragment of human IgM.
产品特性 The purified antibody is conjugated with Horseradish Peroxidase (HRP) of high specific activity and RZ=3.
背景 Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days.
分子量 900 kDa
研究领域 Secondary Antibodies
应用备注 The antibody is designed for Western blotting analysis. Suggested working concentration is 4 µg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Working concentrations should be determined by the investigator.
限制 仅限研究用
状态 Liquid
浓度 1 mg/mL
缓冲液 The reagent is provided in phosphate buffered saline (PBS) containing 0.01 % (w/v) thimerosal and 1 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
储存液 Thimerosal (Merthiolate)
注意事项 Biohazard Informations: This product contains thimerosal which is hazardous.
注意事项 Do not freeze.
Avoid prolonged exposure to light.
储存条件 4 °C
储存方法 Store in the dark at 2-8 °C. Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
厂商提供的图像
Flow Cytometry (FACS) image for 小鼠 anti-人 IgM (Fc Region) Antibody (HRP) (ABIN457359) Surface staining of human peripheral blood cells with anti-human IgM (CH2) APC. Cells...
背景 Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." in: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." in: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." in: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).