TSPO 抗体 (C-Term)
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- 抗原 See all TSPO 抗体
- TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This TSPO antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 序列
- c-RDNHGWRGGR RLPE
- 特异性
- This antibody is expected to recognise one isoform of TSPO/PBR (NP_000705.2) only.
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- 免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_000705.2. Genename: TSPO
- Top Product
- Discover our top product TSPO Primary Antibody
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anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (C-Term) antibody
Verified TSPO 适用: 小鼠 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) antibodyTSPO 适用: 人 WB, ELISA, IHC, IP, IF, FACS 宿主: 兔 Monoclonal 23G2 unconjugated Recombinant Antibody
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (C-Term) antibodyVerified TSPO 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) antibodyTSPO 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (C-Term) antibodyTSPO 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (AA 1-169) antibodyTSPO 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (AA 1-169) antibodyTSPO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D8-B2 unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (AA 1-50) antibodyTSPO 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (AA 12-85) antibodyTSPO 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral-Type Benzodiazepine Receptor (TSPO) (AA 1-169) antibodyTSPO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Peptide ELISA: Detection Limit: 1/128000. Western blot: 0.1-0.3 μg/mL. Approx 35 kDa band observed in Human Brain lysates(calculated MW of 18.5 kDa according to NP_000705.2). Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Colon shows strongcytoplasm staining of absorptive cells.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))
- 别名
- TSPO / BZRP (TSPO 产品)
- 别名
- LOC732875 antibody, LOC100136652 antibody, LOC100280949 antibody, BZRP antibody, TSPO antibody, Bzrp antibody, IBP antibody, PBR antibody, Tspo1 antibody, MBR antibody, PTBZR02 antibody, Ptbzr antibody, RATPTBZR02 antibody, BPBS antibody, DBI antibody, PBS antibody, PKBS antibody, PTBR antibody, mDRC antibody, pk18 antibody, peripheral-type benzodiazepine receptor antibody, Peripheral-type benzodiazepine receptor antibody, putative peripheral-type benzodiazepine receptor antibody, translocator protein antibody, translocator protein homolog antibody, hypothetical protein antibody, LOC732875 antibody, MAV_3896 antibody, xccb100_2086 antibody, Smp_102510 antibody, Sros_1911 antibody, tspo antibody, LOC100280949 antibody, PGTG_16395 antibody, TSPO antibody, Tspo antibody
- 背景
- PBR (Peripheral type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid producing tissues and is found in association with a 34 kDa voltage dependent anion channel protein (VDAC). PBR interacts with some benzodiazepines and has different affinities than its endogenous counterpart. PBR appears to be a key factor in the transport of cholesterol from the outer to the inner mitochondrial membrane to permit the initiation of steroid hormone synthesis. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis. It is speculated that patients with congenital lipoid adrenal hyperplasia, who cannot make any steroids, might have a genetic lesion in BZRP. A short form, PBRS is also expressed in the same tissues, but at a level about ten times that of PBR.Synonyms: MBR, Mitochondrial benzodiazepine receptor, PBR, PKBS, Peripheral-type benzodiazepine receptor, Translocator protein
- 基因ID
- 706
- NCBI登录号
- NP_000705
- UniProt
- P30536
- 途径
- Cellular Response to Molecule of Bacterial Origin
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