ATP6V1C1 抗体 (N-Term)
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Quick Overview for ATP6V1C1 抗体 (N-Term) (ABIN406715)
抗原
See all ATP6V1C1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ldafvegvvk kvaqymadvl edskdkvqen llangvdlvt yitrfqwdma
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ATP6V1C1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V1C1
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anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) antibody
ATP6V1C1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) (AA 129-382) antibodyATP6V1C1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) (AA 1-382) antibodyATP6V1C1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) (AA 1-110) antibodyATP6V1C1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) (AA 61-110) antibodyATP6V1C1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, Bat, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) (N-Term) antibodyATP6V1C1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1) (N-Term) antibodyATP6V1C1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 382 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy." in: Oncotarget, Vol. 6, Issue 29, pp. 28057-70, (2015) (PubMed).
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- ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))
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别名
- ATP6V1C1
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背景
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ATP6V1C1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATP6C, ATP6D, FLJ20057, VATC, Vma5
Protein Interaction Partner: ATP6V1C1, IVNS1ABP, ATG7, DNM1L, TSN, STAT1, SNX2, SNX1, SHMT2, SHMT1, SARS, RDX, PAWR, NASP, IDE, GTF2A1, GSPT1, CTTN, PSMG3, ANP32E, TBC1D15, SNX6, VPS35, VPS29, LUC7L2, VTA1, ARFIP1, GSPT2, UBC, UBAC2, TXNDC17, MRPS35, CISD1, VASP, TYMS, SSR1, SRSF5, A
Protein Size: 382 -
分子量
- 42 kDa
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基因ID
- 528
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NCBI登录号
- NM_001695, NP_001686
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UniProt
- P21283
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途径
- Transition Metal Ion Homeostasis, Proton Transport
抗原
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