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SEMA6D 抗体 (N-Term)

SEMA6D 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN406054
发货至: 中国
  • 抗原 See all SEMA6D 抗体
    SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))
    抗原表位
    • 15
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    • 4
    • 1
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    • 1
    N-Term
    适用
    • 36
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    • 4
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    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠, Pig
    宿主
    • 49
    • 2
    克隆类型
    • 51
    多克隆
    标记
    • 18
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    This SEMA6D antibody is un-conjugated
    应用范围
    • 26
    • 20
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    KLYSATVADF LASDAVIYRS MGDGSALRTI KYDSKWIKEP HFLHAIEYGN
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against SEMA6D. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SEMA6D
    Top Product
    Discover our top product SEMA6D Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 597 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))
    别名
    SEMA6D (SEMA6D 产品)
    别名
    1110067B02Rik antibody, AA409156 antibody, D330011G23 antibody, Sema6D-1 antibody, Sema6D-2 antibody, Sema6D-4 antibody, Sema6D-5 antibody, Sema6D-6 antibody, mKIAA1479 antibody, wu:fi06a12 antibody, wu:fi76a10 antibody, zgc:56170 antibody, semaphorin 6D antibody, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D antibody, semaphorin 6D L homeolog antibody, SEMA6D antibody, Sema6d antibody, sema6d antibody, sema6d.L antibody
    背景
    Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
    Alias Symbols: FLJ11598, KIAA1479
    Protein Interaction Partner: PLXNA1,
    Protein Size: 597
    分子量
    65 kDa
    基因ID
    80031
    NCBI登录号
    NM_153619, NP_705872
    UniProt
    A6NM95
    途径
    Smooth Muscle Cell Migration
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