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WNT6 抗体 (Middle Region)

WNT6 适用: 人, 小鼠, 兔, 大鼠, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN405845
发货至: 中国
  • 抗原 See all WNT6 抗体
    WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 44
    • 23
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 兔, 大鼠, Cow, 犬, 豚鼠
    宿主
    • 43
    • 1
    • 1
    克隆类型
    • 45
    多克隆
    标记
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNT6 antibody is un-conjugated
    应用范围
    • 42
    • 20
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    ERFHGASRVM GTNDGKALLP AVRTLKPPGR ADLLYAADSP DFCAPNRRTG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against WNT6. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human WNT6
    Top Product
    Discover our top product WNT6 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 365 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
    别名
    WNT6 (WNT6 产品)
    别名
    WNT6 antibody, si:dkey-31m21.2 antibody, Wnt6 antibody, AA409270 antibody, Wnt-6 antibody, Xwnt-6 antibody, wnt-6 antibody, wnt6-A antibody, xWnt6 antibody, Wnt family member 6 antibody, wingless-type MMTV integration site family, member 6b antibody, wingless-type MMTV integration site family, member 6 antibody, Wnt family member 6 S homeolog antibody, WNT6 antibody, Wnt6 antibody, wnt6b antibody, wnt6.S antibody
    背景
    The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
    Alias Symbols: -
    Protein Interaction Partner: PORCN,
    Protein Size: 365
    分子量
    37 kDa
    基因ID
    7475
    NCBI登录号
    NM_006522, NP_006513
    UniProt
    Q9Y6F9
    途径
    WNT signaling, Tube Formation
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