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Keratin 10 抗体 (N-Term)

KRT10 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN405420
发货至: 中国
  • 抗原 See all Keratin 10 (KRT10) 抗体
    Keratin 10 (KRT10)
    抗原表位
    • 16
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 121
    • 57
    • 50
    • 27
    • 18
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马
    宿主
    • 75
    • 49
    • 2
    克隆类型
    • 68
    • 58
    多克隆
    标记
    • 72
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratin 10 antibody is un-conjugated
    应用范围
    • 80
    • 56
    • 53
    • 39
    • 34
    • 27
    • 15
    • 14
    • 13
    • 11
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    EKVTMQNLND RLASYLDKVR ALEESNYELE GKIKEWYEKH GNSHQGEPRD
    预测反应
    Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against KRT10. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human KRT10
    Top Product
    Discover our top product KRT10 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 584 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tsubota, Akiyama, Kanitakis, Sakai, Nomura, Claudy, Shimizu: "Mild recessive bullous congenital ichthyosiform erythroderma due to a previously unidentified homozygous keratin 10 nonsense mutation." in: The Journal of investigative dermatology, Vol. 128, Issue 7, pp. 1648-52, (2008) (PubMed).

  • 抗原
    Keratin 10 (KRT10)
    别名
    KRT10 (KRT10 产品)
    别名
    BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, D130054E02Rik antibody, K1C1 antibody, Krt-1.10 antibody, Krt1-10 antibody, Ka10 antibody, Ker10 antibody, KRT10 antibody, KRT25 antibody, KRT27 antibody, KRT28 antibody, keratin 10 antibody, keratin 10, type I S homeolog antibody, keratin, type I cytoskeletal 25 antibody, KRT10 antibody, Krt10 antibody, krt10.S antibody, LOC101085587 antibody
    背景
    KRT10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in the gene encoding KRT10 are associated with epidermolytic hyperkeratosis. This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CK10, K10, KPP, BIE, EHK, BCIE
    Protein Interaction Partner: UBC, Fbxl16, ADRB2, PAN2, Nphp4, Iqcb1, Cep290, Nphp1, Invs, VCAM1, SRC, ITGA4, FN1, ALB, MAGOH, TRAF3IP1, EIF4A3, AHNAK2, KRT2, KRT1, ELAVL1, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, NEDD8, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CU
    Protein Size: 584
    分子量
    59 kDa
    基因ID
    3858
    NCBI登录号
    NM_000421, NP_000412
    UniProt
    P13645
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