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KDM6A 抗体 (Middle Region)

KDM6A 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN405243
发货至: 中国
  • 抗原 See all KDM6A 抗体
    KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
    抗原表位
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 32
    • 11
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔
    宿主
    • 23
    • 13
    克隆类型
    • 23
    • 13
    多克隆
    标记
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KDM6A antibody is un-conjugated
    应用范围
    • 23
    • 14
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    KTYIVHCQDC ARKTSGNLEN FVVLEQYKME DLMQVYDQFT LAPPLPSASS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against UTX. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human UTX
    Top Product
    Discover our top product KDM6A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1401 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
    别名
    UTX (KDM6A 产品)
    别名
    KABUK2 antibody, UTX antibody, bA386N14.2 antibody, Utx antibody, si:ch211-222m21.1 antibody, utx antibody, kdm6a antibody, tutx antibody, uty antibody, xtutx antibody, lysine demethylase 6A antibody, lysine-specific demethylase 6A antibody, lysine (K)-specific demethylase 6A antibody, lysine demethylase 6A S homeolog antibody, KDM6A antibody, LOC100539898 antibody, Kdm6a antibody, kdm6a antibody, kdm6a.S antibody
    背景
    UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
    Alias Symbols: DKFZp686A03225, MGC141941, bA386N14.2, UTX, KABUK2
    Protein Interaction Partner: KMT2D, WDR5, ASH2L, RBBP5, SMAD9, HIST2H3C, SRF, SMARCA4, GATA4, NKX2-5, TBX5, UBC, HIST1H3A, WDR82, PAXIP1, NCOA6, TLE1, PROSER1, KMT2C, N4BP2, PPP6R3, ZNF281, HIST3H3,
    Protein Size: 1401
    分子量
    154 kDa
    基因ID
    7403
    NCBI登录号
    NM_021140, NP_066963
    UniProt
    O15550
    途径
    Tube Formation, Warburg Effect
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