PIK3R1 抗体 (pTyr199, pTyr464, pTyr467)
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- 抗原 See all PIK3R1 (PI3K p85a) 抗体
- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
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抗原表位
- pTyr199, pTyr464, pTyr467
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIK3R1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of total PI3K P85 alpha/gamma/beta protein.
- 纯化方法
- Immunoaffinity Chromatography using epitope-specific immunogen.
- 免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human PI3K P85 alpha/gamma/beta around the phosphorylation site of Tyrosine 467/199/464 (L-Yp-E-E-Y).
- Top Product
- Discover our top product PI3K p85a Primary Antibody
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anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-454) antibody
PI3K p85a 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr607) antibodyPI3K p85a 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibodyPI3K p85a 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6G10 unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 501-600) antibodyPI3K p85a 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-30), (N-Term) antibodyPI3K p85a 适用: 人, 大鼠 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB11634 unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibodyPI3K p85a 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr607) antibodyPI3K p85a 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 15-180) antibodyPI3K p85a 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibodyPI3K p85a 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibodyPI3K p85a 适用: 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 3B7 unconjugated
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- 应用备注
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Immunohistochemistry on Paraffin Sections: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at-20 °C.
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- 抗原
- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
- 别名
- PIK3R1 / GRB1 (PI3K p85a 产品)
- 别名
- PI3CG antibody, PI3K antibody, PI3Kgamma antibody, PIK3 antibody, AGM7 antibody, GRB1 antibody, p85 antibody, p85-ALPHA antibody, PI3KA antibody, AA414921 antibody, C530050K14 antibody, p50alpha antibody, p55alpha antibody, p85alpha antibody, wu:fb65b05 antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma antibody, phosphoinositide-3-kinase regulatory subunit 1 antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta antibody, phosphoinositide-3-kinase, regulatory subunit 1 (alpha) antibody, PIK3CG antibody, PIK3R1 antibody, Pik3r1 antibody, Pik3cb antibody, pik3r1 antibody
- 背景
- The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.Synonyms: GRB1, PIK3R1, PIK3R2, PIK3R3, Phosphatidylinositol 3-kinase regulatory subunit alpha, beta, gamma
- 基因ID
- 5295
- NCBI登录号
- NP_852556
- UniProt
- P27986
- 途径
- TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect
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