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MEF2A 抗体 (pThr319)

MEF2A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401542
发货至: 中国
  • 抗原 See all MEF2A 抗体
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    抗原表位
    • 20
    • 18
    • 14
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pThr319
    适用
    • 125
    • 98
    • 79
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
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    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 122
    • 5
    克隆类型
    • 111
    • 16
    多克隆
    标记
    • 65
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MEF2A antibody is un-conjugated
    应用范围
    • 95
    • 42
    • 40
    • 33
    • 26
    • 26
    • 21
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
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    Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of MEF2A only when phosphorylated at Thr319.
    纯化方法
    Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from Human MEF2A around the phosphorylation site of Thr319 (V-T-TP-P-S).
    Top Product
    Discover our top product MEF2A Primary Antibody
  • 应用备注
    Immunofluorescence: 1/100approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at-20 °C.
  • 抗原
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    别名
    MEF2A (MEF2A 产品)
    别名
    ADCAD1 antibody, RSRFC4 antibody, RSRFC9 antibody, mef2 antibody, A430079H05Rik antibody, mef2a antibody, wu:fd19d02 antibody, adcad1 antibody, rsrfc4 antibody, rsrfc9 antibody, sl2 antibody, MEF2A antibody, xmef2a antibody, myocyte enhancer factor 2A antibody, myocyte enhancer factor 2aa antibody, myocyte enhancer factor 2a antibody, myocyte-specific enhancer factor 2A antibody, myocyte-specific enhancer factor 2a, putative antibody, myocyte enhancer factor 2A L homeolog antibody, MEF2A antibody, Mef2a antibody, mef2aa antibody, EDI_092490 antibody, EDI_038250 antibody, Smp_161530 antibody, mef2a.L antibody, mef2a antibody, LOC539054 antibody
    背景
    The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF-4, are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.Synonyms: MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1
    基因ID
    4205
    NCBI登录号
    NP_001124398
    UniProt
    Q02078
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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