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RPS6KA1 抗体 (C-Term, pSer732)

RPS6KA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 小鸡, Opossum WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401473
发货至: 中国
  • 抗原 See all RPS6KA1 抗体
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    抗原表位
    • 41
    • 30
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    C-Term, pSer732
    适用
    • 206
    • 123
    • 91
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 小鸡, Opossum
    宿主
    • 216
    • 17
    克隆类型
    • 193
    • 41
    多克隆
    标记
    • 107
    • 17
    • 14
    • 11
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    • 4
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    • 1
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    This RPS6KA1 antibody is un-conjugated
    应用范围
    • 185
    • 104
    • 54
    • 53
    • 50
    • 27
    • 25
    • 25
    • 15
    • 12
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific for p90 RSK1 protein phosphorylated at S732.
    交叉反应 (详细)
    Species reactivity (expected):Rat, Mouse, Horse, Bovine, Canine, Opossum, Chicken.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide corresponding to a region near the C-terminal end of human RSK1 protein
    亚型
    IgG
    Top Product
    Discover our top product RPS6KA1 Primary Antibody
  • 应用备注
    ELISA: 1/100,000. Western Blot: 1/500 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.64 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    别名
    RPS6KA1 (RPS6KA1 产品)
    别名
    HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, Rsk1 antibody, p90rsk antibody, rsk antibody, RPS6KA antibody, hu-1 antibody, mapkapk1a antibody, rsk1 antibody, wu:fc56h07 antibody, zgc:152654 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase polypeptide 1 antibody, ribosomal protein S6 kinase A1-like antibody, ribosomal protein S6 kinase A1 L homeolog antibody, ribosomal protein S6 kinase a, polypeptide 1 antibody, RPS6KA1 antibody, Rps6ka1 antibody, RPS6KA1L antibody, rps6ka1.L antibody, rps6ka1 antibody
    背景
    Ribosomal S6 Kinase 1 (RSK1, S6K-alpha 1, 90 kDa Ribosomal Protein S6 Kinase 1, MAP kinase-activated protein kinase 1a, or MAPKAPK1A) is an immediate downstream effector of mitogen activated protein kinases and therefore promotes cell proliferation and survival. It has serine/threonine kinase activity and may play a role in mediating the growth-factor and stress-induced activation of the transcription factor CREB. The C-terminal region of RSK1 is reported to be an ERK docking site, where serine 732 phosphorylation status is critical for RSK1 activation. When serine 732 is not phosphorylated, ERK1/2 binds to the ERK docking site of RSK1, and upon stimulation, activates RSK1. The activated RSK1 then autophosphorylates serine 732, leading to the dissociation of ERK from RSK1 and termination of activation by ERK.Synonyms: 90 kDa ribosomal protein S6 kinase 1, MAPKAPK1A, RSK-1, RSK1, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase alpha-1, p90RSK1
    基因ID
    6195
    NCBI登录号
    NP_001006666
    UniProt
    Q15418
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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