NCOA3 抗体 (Internal Region, Isoform A)
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- 抗原 See all NCOA3 抗体
- NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
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抗原表位
- Internal Region, Isoform A
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适用
- 人, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCOA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts with several isoforms of NCOA3 protein (a, b, d, e and f).
- 交叉反应 （详细）
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Species reactivity (expected):Marcaque, Canine, Bovine, Mouse, Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 免疫原
- Synthetic peptide corresponding to an internal region of human NCOA3 isoform a protein
- 亚型
- IgG
- Top Product
- Discover our top product NCOA3 Primary Antibody
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anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 1023-1304) antibody
NCOA3 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) antibodyNCOA3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (Internal Region) antibodyNCOA3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 188-198) antibodyNCOA3 适用: 人, Cow, 犬, Pig, 猴, Bat, Hamster IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 576-625) antibodyNCOA3 适用: 人, Cow, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) antibodyNCOA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5H3 unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (pThr24) antibodyNCOA3 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 344-372), (N-Term) antibodyNCOA3 适用: 人 WB 宿主: 兔 Polyclonal RB41497 unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) antibodyNCOA3 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 1-200) antibodyNCOA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C11B12 unconjugated
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- 应用备注
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ELISA: 1/175000. Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.24 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
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- 抗原
- NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
- 别名
- NCOA3 (NCOA3 产品)
- 别名
- NCOA3 antibody, ACTR antibody, AIB-1 antibody, AIB1 antibody, CAGH16 antibody, CTG26 antibody, KAT13B antibody, RAC3 antibody, SRC-3 antibody, SRC3 antibody, TNRC14 antibody, TNRC16 antibody, TRAM-1 antibody, bHLHe42 antibody, pCIP antibody, 2010305B15Rik antibody, AW321064 antibody, Actr antibody, Aib1 antibody, Rac3 antibody, Src3 antibody, Tram-1 antibody, Tram1 antibody, p/Cip antibody, pCip antibody, actr antibody, aib-1 antibody, aib1 antibody, cagh16 antibody, ctg26 antibody, kat13b antibody, pcip antibody, rac3 antibody, src-3 antibody, src3 antibody, tnrc14 antibody, tnrc16 antibody, tram-1 antibody, xSRC-3 antibody, nuclear receptor coactivator 3 antibody, nuclear receptor coactivator 3 S homeolog antibody, NCOA3 antibody, Ncoa3 antibody, ncoa3.S antibody
- 背景
- The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). NCOA3 is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. This antibody was raised against variant 1 which is the longer isoform (a). In addition, a polymorphic repeat region is found in the C-terminus of the protein.Synonyms: ACTR, AIB-1, AIB1, Amplified in breast cancer 1 protein, BHLHE42, CBP-interacting protein, Class E basic helix-loop-helix protein 42, NCoA-3, Nuclear receptor coactivator 3, RAC-3, RAC3, Receptor-associated coactivator 3, SRC-3, Steroid receptor coactivator protein 3, TRAM-1, TRAM1, Thyroid hormone receptor activator molecule 1, pCIP
- 基因ID
- 8202
- NCBI登录号
- NP_001167559
- UniProt
- Q9Y6Q9
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
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