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MARK2 抗体 (Isoform A, pThr595)

MARK2 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401318
发货至: 中国
  • 抗原 See all MARK2 抗体
    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
    抗原表位
    • 13
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform A, pThr595
    适用
    • 73
    • 49
    • 40
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬
    宿主
    • 69
    • 3
    • 1
    克隆类型
    • 62
    • 11
    多克隆
    标记
    • 36
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MARK2 antibody is un-conjugated
    应用范围
    • 50
    • 37
    • 22
    • 16
    • 11
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against the phosphorylated form of MARK2 at thepT595 residue.
    交叉反应 (详细)
    Species reactivity (expected):Canine, Bovine, Mouse, Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide corresponding to amino acids surrounding T595 of Human MARK2 isoform a. The immunogen peptide was phosphorylated at the residue corresponding to T595
    亚型
    IgG
    Top Product
    Discover our top product MARK2 Primary Antibody
  • 应用备注
    ELISA: 1/1,000 - 1/3,000. Western Blot: 1/250 - 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.6 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
    别名
    MARK2 (MARK2 产品)
    别名
    EMK-1 antibody, EMK1 antibody, PAR-1 antibody, Par-1b antibody, Par1b antibody, AU024026 antibody, Emk antibody, Par-1 antibody, mKIAA4207 antibody, microtubule affinity regulating kinase 2 antibody, MAP/microtubule affinity regulating kinase 2 antibody, MARK2 antibody, Mark2 antibody
    背景
    This antibody recognizes a regulatory phosphorylation on a kinase that is critical to regulation of microtubules, cell cycle and immune responses. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encode two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gives rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be co-expressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA that is ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.Synonyms: 2, ELKL motif kinase, EMK1, MAP/microtubule affinity-regulating kinase, MARK2, PAR1 homolog, Serine/threonine-protein kinase
    基因ID
    2011
    NCBI登录号
    NP_001034558
    UniProt
    Q7KZI7
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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