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MAD2L1 抗体 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 1-206)

Details for Product anti-MAD2L1 Antibody No. ABIN395553, 供应商: Log in to see
抗原
  • cb408
  • zgc:112133
  • MAD2L1
  • mad2
  • XMad2
  • AA673185
  • MAD2
  • HSMAD2
  • MAD2 mitotic arrest deficient-like 1 (yeast)
  • MAD2 mitotic arrest deficient-like 1
  • MAD2L1
  • mad2l1
  • LOC100218172
  • Mad2l1
抗原表位
AA 1-206
19
7
7
6
4
4
4
3
3
3
2
2
1
1
1
1
1
1
适用

120
36
33
9
6
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4
4
4
3
3
2
2
1
宿主
小鼠
72
33
15
1
克隆类型 (克隆位点)
单克隆 ()
标记
This MAD2L1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
102
46
23
22
21
20
13
6
2
1
1
1
1
1
Supplier
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Available images

免疫原 MAD2L1 (AAH00356, 1 a.a. ~ 206 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
克隆位点 2E2-1D6
亚型 IgG2b kappa
特异性 MAD2L1 (AAH00356, 1 a.a. ~ 206 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
纯化方法 This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
别名 MAD2L1 (MAD2L1 Antibody 摘要)
背景 Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
分子量 23510 DA
基因ID 12406
研究领域 Cell Cycle, Cell Structure
应用备注 Western blot = 1:500-1000
说明

Background: MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

限制 仅限研究用
浓度 0.5 mg/ml
缓冲液 PBS with 0.09% (w/v) sodium azide.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
有效期 6 months
厂商提供的图像
Western Blotting (WB) image for anti-MAD2L1 抗体 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 1-206) (ABIN395553) MAD2L1 monoclonal antibody (M01), clone 2E2-1D6 Western Blot analysis of MAD2L1 expre...
Immunohistochemistry (IHC) image for anti-MAD2L1 抗体 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 1-206) (ABIN395553) anti-MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) (AA 1-206) antibody (Image 2)
背景 Hewitt, Tighe, Santaguida, White, Jones, Musacchio, Green, Taylor: "Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex." in: The Journal of cell biology, Vol. 190, Issue 1, pp. 25-34, 2010 (PubMed).

Guo, Zhang, Yang, Miao, Shi, Yao, Tan, Sun, Zhao, Yu, Liu, Lin: "Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer." in: Journal of medical genetics, Vol. 47, Issue 9, pp. 616-22, 2010 (PubMed).

Gladhaug, Westgaard, Schjølberg, Burum-Auensen, Pomianowska, Clausen: "Spindle proteins in resected pancreatic head adenocarcinomas: BubR1 is an independent prognostic factor in pancreatobiliary-type tumours." in: Histopathology, Vol. 56, Issue 3, pp. 345-55, 2010 (PubMed).

Wang, Yin, Du, Chen, Liang, Zhang, Du, Wu, Ding, Fan: "Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin." in: Tumour biology, Vol. 31, Issue 3, pp. 225-32, 2010 (PubMed).

Kalsi, Kuo, Aliev, Alexander, McMichael, Patterson, Walsh, Zhao, Schuckit, Nurnberger, Edenberg, Kramer, Hesselbrock, Tischfield, Vladimirov, Prescott, Dick, Kendler, Riley: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, 2010 (PubMed).