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ULK2 抗体 (N-Term)

ULK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12561 unconjugated
产品编号 ABIN392692
发货至: 中国
  • 抗原 See all ULK2 抗体
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    抗原表位
    • 12
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-264, N-Term
    适用
    • 73
    • 18
    • 8
    宿主
    • 65
    • 9
    克隆类型
    • 66
    • 8
    多克隆
    标记
    • 35
    • 8
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULK2 antibody is un-conjugated
    应用范围
    • 58
    • 50
    • 15
    • 15
    • 14
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ULK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the N-terminal region of human ULK2.
    克隆位点
    RB12561
    亚型
    Ig Fraction
    Top Product
    Discover our top product ULK2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    别名
    ULK2 (ULK2 产品)
    别名
    ULK2 antibody, ATG1B antibody, Unc51.2 antibody, A830085I22Rik antibody, AU015340 antibody, mKIAA0623 antibody, unc-51 like autophagy activating kinase 2 antibody, unc-51 like kinase 2 antibody, ULK2 antibody, Ulk2 antibody, ulk2 antibody
    背景
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Two human homologs of the yeast autophagy-specific kinase exist: ULK1(APG1) and ULK2. APG1 plays a critical role in regulating key elements of the autophagy pathway. APG1 stimulates autophagy, leading to autophagy-dependent restriction of cell growth and ultimately cell apoptosis at high levels of activity, and is a negative regulator of mTOR signaling.
    分子量
    112694
    基因ID
    9706
    NCBI登录号
    NP_001136082, NP_055498
    UniProt
    Q8IYT8
    途径
    Regulation of Cell Size, Autophagy
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