NEK9 抗体 (C-Term)
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Quick Overview for NEK9 抗体 (C-Term) (ABIN392654)
抗原
See all NEK9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 846-877, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This NEK9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-877 amino acids from the C-terminal region of human NEK9.
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亚型
- Ig Fraction
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anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 226-326) antibody
NEK9 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyKD Validated NEK9 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB6355 unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 730-979) antibodyNEK9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyNEK9 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 821-979) antibodyNEK9 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyNEK9 适用: 人, 马, 兔, Pig, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (Kinase Domain) antibodyNEK9 适用: 人, 小鼠, 马, 兔, Cow, Pig, 猴, Bat, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (Internal Region) antibodyNEK9 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 1-979) antibodyNEK9 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 1-979) antibodyNEK9 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- NEK9 (NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9))
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别名
- NEK9
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背景
- NEK9, a member of the NIMA subfamily of Ser/Thr protein kinases, is a pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. It phosphorylates different histones (serine and threonine residues on H3), myelin basic protein, beta-casein (serine residues), and BICD2. NEK9 is activated during mitosis by intramolecular autophosphorylation. Activity and autophosphorylation is activated by manganese >> magnesium ions, and is sensitive to increasing concentration of detergents. This protein is not cell-cycle regulated but activity is higher in G0-arrested cells. NEK is part of a homodimer that binds to Ran GTPase, and exhibits a greater affinity for Ran-GDP over Ran-GTP. Interaction is also noted with NEK6 and NEK7 family members. This cytoplasmic protein is most abundant in heart, liver, kidney and testis, and is also expressed in smooth muscle cells and fibroblasts. Expression varies mildly across the cell cycle, with highest expression observed in G1 and stationary-phase cells.
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分子量
- 107168
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基因ID
- 91754
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NCBI登录号
- NP_149107
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UniProt
- Q8TD19
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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