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ZAK 抗体 (AA 271-300)

ZAK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03313-03314 unconjugated
产品编号 ABIN392643
发货至: 中国
  • 抗原 See all ZAK 抗体
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    抗原表位
    • 15
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-300
    适用
    • 41
    • 34
    • 18
    • 2
    宿主
    • 51
    • 6
    克隆类型
    • 51
    • 6
    多克隆
    标记
    • 31
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZAK antibody is un-conjugated
    应用范围
    • 30
    • 24
    • 14
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This MLKLAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human MLKLAK.
    克隆位点
    RB03313-03314
    亚型
    Ig Fraction
    Top Product
    Discover our top product ZAK Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Pescatore, Esposito, Draber, Walczak, Ursini: "NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II." in: Cell death & disease, Vol. 7, Issue 8, pp. e2346, (2017) (PubMed).

  • 抗原
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    别名
    MLKLAK (ZAK 产品)
    别名
    MLTK antibody, RGD1561394 antibody, AZK antibody, MLK7 antibody, MLT antibody, MRK antibody, mlklak antibody, pk antibody, AV006891 antibody, B230120H23Rik antibody, MLTKalpha antibody, MLTKbeta antibody, mitogen-activated protein kinase kinase kinase 20 antibody, Map3k20 antibody, MAP3K20 antibody
    背景
    MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.
    分子量
    91155
    基因ID
    51776
    NCBI登录号
    NP_057737, NP_598407
    UniProt
    Q9NYL2
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