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RPS6KB2 抗体 (C-Term)

RPS6KB2 适用: 人 WB 宿主: 兔 Polyclonal RB0891 unconjugated
产品编号 ABIN392546
发货至: 中国
  • 抗原 See all RPS6KB2 抗体
    RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))
    抗原表位
    • 16
    • 16
    • 15
    • 15
    • 15
    • 12
    • 11
    • 11
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 452-482, C-Term
    适用
    • 102
    • 68
    • 63
    • 12
    • 12
    • 11
    • 10
    • 2
    • 2
    宿主
    • 147
    • 14
    • 1
    克隆类型
    • 148
    • 14
    多克隆
    标记
    • 56
    • 13
    • 12
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    This RPS6KB2 antibody is un-conjugated
    应用范围
    • 123
    • 69
    • 53
    • 53
    • 27
    • 21
    • 20
    • 14
    • 10
    • 6
    • 6
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This p70 S6Kbeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human p70 S6Kbeta.
    克隆位点
    RB0891
    亚型
    Ig Fraction
    Top Product
    Discover our top product RPS6KB2 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Wang, Li, Du, Xu, Wang, Zhang, Xu, Zeng, Mao, Cao: "The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex." in: Journal of pharmacological sciences, Vol. 134, Issue 4, pp. 197-202, (2018) (PubMed).

    Kroczynska, Mehrotra, Majchrzak-Kita, Arslan, Altman, Stein, McMahon, Kozlowski, Kahle, Eklund, Fish, Platanias: "Regulatory effects of SKAR in interferon ? signaling and its role in the generation of type I IFN responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11377-82, (2014) (PubMed).

    Cruz, Hedden, Boyer, Kharas, Fruman, Lee-Fruman: "S6 kinase 2 potentiates interleukin-3-driven cell proliferation." in: Journal of leukocyte biology, Vol. 78, Issue 6, pp. 1378-85, (2005) (PubMed).

  • 抗原
    RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))
    别名
    p70 S6Kbeta (RPS6KB2 产品)
    别名
    KLS antibody, P70-beta antibody, P70-beta-1 antibody, P70-beta-2 antibody, S6K-beta2 antibody, S6K2 antibody, SRK antibody, STK14B antibody, p70(S6K)-beta antibody, p70S6Kb antibody, 70kDa antibody, ribosomal protein S6 kinase B2 antibody, ribosomal protein S6 kinase, polypeptide 2 antibody, RPS6KB2 antibody, Rps6kb2 antibody
    背景
    This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
    分子量
    53455
    基因ID
    6199
    NCBI登录号
    NP_003943
    UniProt
    Q9UBS0
    途径
    PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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