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PRKG1 抗体 (C-Term)

PRKG1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1046 unconjugated
产品编号 ABIN392536
发货至: 中国
  • 抗原 See all PRKG1 抗体
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 629-660, C-Term
    适用
    • 42
    • 26
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 36
    • 6
    克隆类型
    • 38
    • 4
    多克隆
    标记
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKG1 antibody is un-conjugated
    应用范围
    • 35
    • 24
    • 16
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This cGKI (cGKI beta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-660 amino acids from the C-terminal region of human cGKI beta.
    克隆位点
    RB1046
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Schwappacher, Kilic, Kojonazarov, Lang, Diep, Zhuang, Gawlowski, Schermuly, Pfeifer, Boss, Pilz: "A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16557-66, (2013) (PubMed).

  • 抗原
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    别名
    cGKI (cGKI beta) (PRKG1 产品)
    别名
    prkg1 antibody, zgc:63955 antibody, Pkgi antibody, cGk1 antibody, 1 antibody, PKG antibody, PRKG1B antibody, PRKGR1B antibody, cGK antibody, cGK 1 antibody, cGK1 antibody, cGKI antibody, cGKI-BETA antibody, cGKI-alpha antibody, CGKI antibody, cGKI-beta antibody, AW125416 antibody, Gm19690 antibody, Prkg1b antibody, Prkgr1b antibody, Prkg1beta antibody, protein kinase, cGMP-dependent, type Ia antibody, protein kinase, cGMP-dependent, type I antibody, protein kinase, cGMP-dependent, type 1 antibody, prkg1a antibody, PRKG1 antibody, prkg1 antibody, Prkg1 antibody
    背景
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
    分子量
    76364
    基因ID
    5592
    NCBI登录号
    NP_001091982, NP_006249
    UniProt
    Q13976
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