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BDNF 抗体 (Brain-Derived Neurotrophic Factor) (AA 206-236)

Details for Product anti-BDNF Antibody No. ABIN392515, 供应商: Log in to see
抗原
  • bdnf-A
  • BDNF
  • Bdnf
  • bdnf
  • ANON2
  • BULN2
  • brain-derived neurotrophic factor
  • brain derived neurotrophic factor
  • brain-derived neurotrophic factor-like
  • bdnf
  • bdnf-A
  • BDNF
  • Bdnf
  • bdnf-b
  • LOC100356949
抗原表位
AA 206-236, C-Term
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适用

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宿主

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克隆类型 (克隆位点)
多克隆 ()
标记
This BDNF antibody is un-conjugated
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应用范围
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Supplier
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免疫原 This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 AA from the C-terminal region of human BDNF.
克隆位点 RB14839
亚型 Ig
特异性 This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214~244 amino acids from the C-terminal region of human BDNF.
预测反应 Cow (Bovine),Mouse (Murine),Pig (Porcine),Rat (Rattus)
纯化方法 This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
别名 BDNF (BDNF Antibody 摘要)
背景 BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders.
Synonyms: Brain-derived neurotrophic factor, BDNF, Abrineurin
分子量 27836 DA
基因ID 627
UniProt P23560
研究领域 Stem Cells, Neurology
途径 RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
应用备注 WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
限制 仅限研究用
状态 Liquid
浓度 2 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months
厂商提供的图像
Western Blotting (WB) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236), (C-Term) antibody (ABIN392515) Western blot analysis of BDNF Antibody (C-term) (ABIN392515) in CEM cell line lysates...
Immunohistochemistry (IHC) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236), (C-Term) antibody (ABIN392515) Formalin-fixed and paraffin-embedded human brain reacted with BDNF Antibody (C-term),...
Flow Cytometry (FACS) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236), (C-Term) antibody (ABIN392515) Flow cytometric analysis of CEM cells using BDNF Antibody (C-term)(bottom histogram) ...
背景 Dmitrzak-Weglarz, Rybakowski, Suwalska, Skibinska, Leszczynska-Rodziewicz, Szczepankiewicz, Hauser: "Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients." in: Pharmacogenomics, Vol. 9, Issue 11, pp. 1595-603, 2008 (PubMed).

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