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RYK 抗体 (AA 160-190)

RYK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1491 unconjugated
产品编号 ABIN392050
发货至: 中国
  • 抗原 See all RYK 抗体
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    抗原表位
    • 11
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-190
    适用
    人, 小鼠, 大鼠
    宿主
    • 71
    • 13
    • 3
    • 1
    克隆类型
    • 77
    • 11
    多克隆
    标记
    • 34
    • 9
    • 9
    • 9
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RYK antibody is un-conjugated
    应用范围
    • 76
    • 54
    • 42
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from human RYK.
    克隆位点
    RB1491
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Povinelli, Nemeth: "Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 1, pp. 105-15, (2014) (PubMed).

    González, Fernández-Martos, Arenas, Rodríguez: "The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury." in: Journal of neurotrauma, Vol. 30, Issue 10, pp. 806-17, (2013) (PubMed).

    Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

    Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: "Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury." in: Journal of neurotrauma, Vol. 26, Issue 7, pp. 955-64, (2009) (PubMed).

  • 抗原
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    别名
    RYK (RYK 产品)
    别名
    RYK antibody, jtk5 antibody, ryk1 antibody, jtk5a antibody, d3s3195 antibody, wu:fb37b12 antibody, wu:fi05b06 antibody, zgc:158381 antibody, MGC114645 antibody, D3S3195 antibody, JTK5 antibody, JTK5A antibody, RYK1 antibody, AW536699 antibody, ERK-3 antibody, Vik antibody, receptor-like tyrosine kinase antibody, receptor-like tyrosine kinase S homeolog antibody, tyrosine-protein kinase RYK antibody, RYK antibody, ryk antibody, ryk.S antibody, LOC100541106 antibody, Ryk antibody
    背景
    RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
    分子量
    67815
    基因ID
    6259
    NCBI登录号
    NP_001005861, NP_002949
    UniProt
    P34925
    途径
    RTK signaling, WNT signaling, Regulation of Cell Size
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