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MME 抗体 (C-Term)

Name: MME 抗体 (C-Term)
SKU: ABIN391499
Availability: OutOfStock

MME 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB18821 unconjugated

Western blot analysis of Neprilysin Antibody (C-term) (ABIN391499 and ABIN2841464) in ,,Ramos cell line lysates (35 μg/lane).

Neprilysin Antibody (C-term) (ABIN391499 and ABIN2841464) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).

FACS

Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

3 images

产品编号 ABIN391499

发货至: 中国

Datasheet as PDF

抗原 See all MME 抗体

MME (Membrane Metallo-Endopeptidase (MME))
抗原表位
16

13

10

8

7

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 506-534, C-Term
适用
205

58

50

3

2

2

2

2

2

1

1

1

1
人
宿主
109

102

2
兔
Compatible Secondaries
克隆类型
108

104

2
多克隆
标记
106

19

18

13

9

6

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
应用范围
130

96

78

67

35

28

21

20

13

13

10

8

6

5

5

3

2

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

M, Rb, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This Neprilysin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human Neprilysin.

克隆位点

RB18821

亚型

Ig Fraction

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anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MME-1870 unconjugated

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MME 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME 适用: 人 WB, IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 FITC

anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME 适用: 人 FACS, WB, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6G12E12 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

MME (Membrane Metallo-Endopeptidase (MME))

别名

Neprilysin (MME 产品)

别名

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

物质类

Chemical

背景

MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

分子量

85514

基因ID

4311

NCBI登录号

NP_000893, NP_009218, NP_009219, NP_009220

UniProt

P08473

途径

RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration