PRKAA2 抗体 (C-Term)
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Quick Overview for PRKAA2 抗体 (C-Term) (ABIN391306)
抗原
See all PRKAA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 476-507, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This AMPK alpha2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-507 amino acids from the C-terminal region of human AMPK alpha2.
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亚型
- Ig Fraction
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anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 453-552) antibody
PRKAA2 适用: 人 WB, ELISA, IF, RNAi, PLA 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (Center) antibodyPRKAA2 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 453-552) antibodyPRKAA2 适用: 人, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8E11H5 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 351-450) antibodyPRKAA2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 1-552) antibodyPRKAA2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 265-294) antibodyPRKAA2 适用: 人 WB 宿主: 兔 Polyclonal RB15728 unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (Internal Region) antibodyVerified PRKAA2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 350-400), (Catalytic Subunit) antibodyPRKAA2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 343-552) antibodyPRKAA2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 252-493) antibodyPRKAA2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
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别名
- AMPK Alpha2
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背景
- AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
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分子量
- 62320
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基因ID
- 5563
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NCBI登录号
- NP_006243
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UniProt
- P54646
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途径
- AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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