PRKAB1 抗体 (N-Term)
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Quick Overview for PRKAB1 抗体 (N-Term) (ABIN391054)
抗原
See all PRKAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 4-34, N-Term
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预测反应
- Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This AMPK beta (PRKAB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human AMPK beta (PRKAB1).
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亚型
- Ig Fraction
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anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibody
PRKAB1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 201-270) antibodyPRKAB1 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer182) antibodyPRKAB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibodyPRKAB1 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer181) antibodyPRKAB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 13-242) antibodyPRKAB1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H12-1A10 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-80) antibodyPRKAB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
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别名
- AMPK beta (PRKAB1)
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背景
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
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分子量
- 30382
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基因ID
- 5564
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NCBI登录号
- NP_006244
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UniProt
- Q9Y478
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途径
- AMPK Signaling, Warburg Effect
抗原
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