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NR4A2 抗体 (N-Term)

Name: NR4A2 抗体 (N-Term)
SKU: ABIN390383
Availability: OutOfStock

NR4A2 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7385 unconjugated

Anti-NURR1 (NR4A2) Antibody (N-term) at 1:1000 dilution + Mouse brain whole tissue lysate Lysates/proteins at 20 μg per lane.

Formalin-fixed and paraffin-embedded human brain tissue reacted with NURR1 (NR4A2) antibody (N-term) (ABIN390383 and ABIN2840784) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

Confocal immunofluorescent analysis of NURR1 (NR4A2) Antibody (N-term) (ABIN390383 and ABIN2840784) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).

3 images

(1 reference)

产品编号 ABIN390383

发货至: 中国

Datasheet as PDF

抗原 See all NR4A2 抗体

NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
抗原表位
15

15

6

3

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 13-42, N-Term
适用
61

45

41

5

5

4

4

4

4

3

2

2

2

2

2

1

1
小鼠
宿主
61

3
兔
Compatible Secondaries
克隆类型
61

3
多克隆
标记
34

3

3

2

2

2

2

2

2

2

2

2

2

2

2
This NR4A2 antibody is un-conjugated
应用范围
61

26

26

17

14

11

8

7

5

4

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

B, Rat

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This NURR1 (NR4A2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human NURR1 (NR4A2).

克隆位点

RB7385

亚型

Ig Fraction

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anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 164-197) antibody
NR4A2 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52431 unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody
NR4A2 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠, 马, 兔, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibody
NR4A2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody
NR4A2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody
NR4A2 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠, 马, 兔, Cow, Pig, 猴, 非洲爪蟾, Bat, 小鸡, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-335) antibody
NR4A2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) antibody
NR4A2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-598) antibody
NR4A2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) antibody
Microarray verified NR4A2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB773479 unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Song, Zukor, Lin, Hascalovici, Liberman, Tavitian, Mui, Vali, Tong, Bhardwaj, Srivastava, Hamel, Schipper: "Schizophrenia-like features in transgenic mice overexpressing human HO-1 in the astrocytic compartment." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 32, pp. 10841-53, (2012) (PubMed).
抗原

NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))

别名

NURR1 (NR4A2) (NR4A2 产品)

别名

nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody

背景

Parkinson's disease (PD) is a multifactorial disease that appears to arise from the effects of both genetic and environmental influences. The known genetic factors include multiple genes that have been identified in related parkinsonian syndromes, as well as alpha-synuclein. Genes associated with either PD or Parkinson-related disorders include parkin, DJ-1, ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1), nuclear receptor-related factor 1 (NURR1), and alpha-synuclein. Nurr1 is a transcription factor that is expressed in the embryonic ventral midbrain and is critical for the development of dopamine (DA) neurons. It belongs to the conserved family of nuclear receptors but lacks an identified ligand and is therefore referred to as an orphan receptor. RXR ligands can promote the survival of DA neurons via a process that depends on Nurr1-RXR heterodimers. In developing DA cells, Nurr1 is required for the expression of several genes important for DA synthesis and function. Nurr1 is also important for the maintenance of adult DA neurons.

分子量

66591

基因ID

4929

NCBI登录号

NP_006177

UniProt

P43354

途径

Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway