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WISP3 抗体 (AA 305-335)

WISP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2145-2146 unconjugated
产品编号 ABIN390189
发货至: 中国
  • 抗原 See all WISP3 抗体
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    抗原表位
    • 15
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 305-335
    适用
    • 24
    • 16
    • 2
    宿主
    • 38
    • 1
    克隆类型
    • 39
    多克隆
    标记
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WISP3 antibody is un-conjugated
    应用范围
    • 29
    • 16
    • 13
    • 13
    • 9
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This WISP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids from the Central region of human WISP3.
    克隆位点
    RB2145-2146
    亚型
    Ig Fraction
    Top Product
    Discover our top product WISP3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Ji, Jia, Jia, Ji, Hargest, Jiang: "WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." in: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).

  • 抗原
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    别名
    WISP3 (WISP3 产品)
    别名
    CCN6 antibody, LIBC antibody, PPAC antibody, PPD antibody, ENSMUSG00000062074 antibody, Gm735 antibody, WISP-3 antibody, RGD1564120 antibody, WISP3 antibody, si:dkey-119m7.6 antibody, WNT1 inducible signaling pathway protein 3 antibody, WISP3 antibody, Wisp3 antibody, wisp3 antibody
    背景
    WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis.
    分子量
    39293
    基因ID
    8838
    NCBI登录号
    NP_003871, NP_937882
    UniProt
    O95389
    途径
    WNT signaling, Growth Factor Binding
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