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SIRT6 抗体 (C-Term)

SIRT6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2109 unconjugated
产品编号 ABIN390181
发货至: 中国
  • 抗原 See all SIRT6 抗体
    SIRT6 (Sirtuin 6 (SIRT6))
    抗原表位
    • 15
    • 15
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-319, C-Term
    适用
    • 91
    • 30
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 87
    • 12
    • 2
    克隆类型
    • 82
    • 19
    多克隆
    标记
    • 52
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRT6 antibody is un-conjugated
    应用范围
    • 82
    • 40
    • 36
    • 14
    • 14
    • 11
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SIRT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 amino acids from the C-terminal region of human SIRT6.
    克隆位点
    RB2109
    亚型
    Ig Fraction
    Top Product
    Discover our top product SIRT6 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:500. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Li, Shi, Yang, Yan, Zhang, Yang, He, Li, Yi, Sun, Liang, Cheng, Shi, Shang, Yu: "SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." in: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).

    Wang, Zhang, Liang, Zhang, Xu, Zhang, Fuji, Mu, Li, Jiang, Ju, Wang: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).

    Wu, Liu, Fu, Liu, Zhou: "Direct evidence of sirtuin downregulation in the liver of non-alcoholic fatty liver disease patients." in: Annals of clinical and laboratory science, Vol. 44, Issue 4, pp. 410-8, (2014) (PubMed).

    Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: "Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer." in: Cancer, Vol. 117, Issue 8, pp. 1670-8, (2011) (PubMed).

  • 抗原
    SIRT6 (Sirtuin 6 (SIRT6))
    别名
    SIRT6 (SIRT6 产品)
    别名
    2810449N18Rik antibody, AI043036 antibody, Sir2l6 antibody, SIR2L6 antibody, zgc:86729 antibody, sirtuin 6 antibody, sirtuin 6 S homeolog antibody, Sirt6 antibody, SIRT6 antibody, sirt6.S antibody, sirt6 antibody
    背景
    SIRT6 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
    分子量
    39119
    基因ID
    51548
    NCBI登录号
    NP_001180214, NP_057623
    UniProt
    Q8N6T7
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