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MAGEA3 抗体 (C-Term)

MAGEA3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB2084 unconjugated
产品编号 ABIN390107
发货至: 中国
  • 抗原 See all MAGEA3 抗体
    MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))
    抗原表位
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 283-314, C-Term
    适用
    • 46
    • 1
    • 1
    宿主
    • 33
    • 12
    • 1
    克隆类型
    • 34
    • 11
    • 1
    多克隆
    标记
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAGEA3 antibody is un-conjugated
    应用范围
    • 35
    • 24
    • 21
    • 15
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This MAGEA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-314 amino acids from the C-terminal region of human MAGEA3.
    克隆位点
    RB2084
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAGEA3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Curioni-Fontecedro, Knights, Tinguely, Nuber, Schneider, Thomson, von Boehmer, Bossart, Pahlich, Gehring, Moch, Renner, Knuth, Zippelius: "MAGE-C1/CT7 is the dominant cancer-testis antigen targeted by humoral immune responses in patients with multiple myeloma." in: Leukemia, Vol. 22, Issue 8, pp. 1646-8, (2008) (PubMed).

    Dubovsky, Albertini, McNeel: "MAD-CT-2 identified as a novel melanoma cancer-testis antigen using phage immunoblot analysis." in: Journal of immunotherapy (Hagerstown, Md. : 1997), Vol. 30, Issue 7, pp. 675-83, (2007) (PubMed).

    Kondo, Zhu, Asa, Ezzat: "The cancer/testis antigen melanoma-associated antigen-A3/A6 is a novel target of fibroblast growth factor receptor 2-IIIb through histone H3 modifications in thyroid cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 16, pp. 4713-20, (2007) (PubMed).

  • 抗原
    MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))
    别名
    MAGEA3 (MAGEA3 产品)
    别名
    CT1.3 antibody, HIP8 antibody, HYPD antibody, MAGE3 antibody, MAGEA6 antibody, Mage-a3 antibody, MAGEA3 antibody, MAGE family member A3 antibody, melanoma antigen, family A, 3 antibody, melanoma antigen family A, 3 antibody, MAGEA3 antibody, Magea3 antibody
    背景
    MAGEA3 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
    分子量
    34747
    基因ID
    4102
    NCBI登录号
    NP_005353
    UniProt
    P43357
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