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CRY1 抗体 (C-Term)

CRY1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1844 unconjugated
产品编号 ABIN390079
发货至: 中国
  • 抗原 See all CRY1 抗体
    CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
    抗原表位
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 556-586, C-Term
    适用
    • 48
    • 20
    • 18
    • 16
    • 15
    • 14
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 6
    • 1
    克隆类型
    • 47
    • 4
    多克隆
    标记
    • 29
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRY1 antibody is un-conjugated
    应用范围
    • 48
    • 23
    • 23
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Pr
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This Cry1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-586 amino acids from the C-terminal region of human Cry1.
    克隆位点
    RB1844
    亚型
    Ig Fraction
    Top Product
    Discover our top product CRY1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Wang, Wang, Liu, Liu, Tay, Walsh, Yang, Wu: "CRISPR/Cas9 mediated genome editing of Helicoverpa armigera with mutations of an ABC transporter gene HaABCA2 confers resistance to Bacillus thuringiensis Cry2A toxins." in: Insect biochemistry and molecular biology, Vol. 87, pp. 147-153, (2017) (PubMed).

  • 抗原
    CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
    别名
    Cry1 (CRY1 产品)
    别名
    cry1-A antibody, CRY1 antibody, cry2 antibody, phll1 antibody, xCRY1 antibody, PHLL1 antibody, AU020726 antibody, AU021000 antibody, Phll1 antibody, ATCRY1 antibody, BLU1 antibody, BLUE LIGHT UNINHIBITED 1 antibody, CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR antibody, ELONGATED HYPOCOTYL 4 antibody, HY4 antibody, OOP2 antibody, OUT OF PHASE 2 antibody, T3H13.14 antibody, T3H13_14 antibody, cryptochrome 1 antibody, cryptochrome circadian clock 1 L homeolog antibody, cryptochrome circadian regulator 1 antibody, cryptochrome circadian clock 1 antibody, Cryptochrome-1 antibody, cryptochrome 1 antibody, cryptochrome 1 (photolyase-like) antibody, cry1.L antibody, CRY1 antibody, cry1 antibody, siu50817b antibody, Cry1 antibody
    背景
    Various biochemical, physiological and behavioural processes display circadian rhythms controlled by an internal biological clock. The central ?gears?driving this clock appear to be composed of an autoregulatory transcription/posttranslation-based feedback loop. Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases. In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function. Mammalian CRY1 and CRY2 function via light-independent interactions with circadian genes CLOCK and BMAL1, as well as with PER1, PER2, and TIM. They seem to act as light-independent components of the circadian clock and likely regulate Per1 transcriptional cycling via interactions with both the activator and its feedback inhibitors. Mutant mice not expressing the Cry1 or Cry2 protein display accelerated and delayed periodicity of locomotor activity, respectively. It appears that the combination of both proteins working together is essential to synchronize the organism to circadian phases. A critical balance between Cry1 and Cry2 is required for proper clock function, in complete darkness, double-mutant mice present with instantaneous arrhythmicity, indicating the absence of an internal circadian clock.
    分子量
    66395
    基因ID
    1407
    NCBI登录号
    NP_004066
    UniProt
    Q16526
    途径
    Response to Water Deprivation, Proton Transport
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