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CDX2 抗体 (N-Term)

CDX2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01821 unconjugated
产品编号 ABIN390076
发货至: 中国
  • 抗原 See all CDX2 抗体
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    抗原表位
    • 21
    • 19
    • 11
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 130
    • 47
    • 42
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 88
    • 39
    • 3
    克隆类型
    • 83
    • 46
    多克隆
    标记
    • 80
    • 10
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDX2 antibody is un-conjugated
    应用范围
    • 80
    • 69
    • 30
    • 30
    • 19
    • 19
    • 15
    • 14
    • 13
    • 13
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This CDX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDX2.
    克隆位点
    RB01821
    亚型
    Ig Fraction
    Top Product
    Discover our top product CDX2 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    别名
    CDX2 (CDX2 产品)
    别名
    CDX2 antibody, MGC130987 antibody, cdx3-like antibody, CDX-3 antibody, CDX3 antibody, CDX-2 antibody, Cdx-2 antibody, caudal type homeobox 2 antibody, caudal type homeobox 2 L homeolog antibody, caudal type homeo box 2 antibody, CDX2 antibody, cdx2.L antibody, Cdx2 antibody
    背景
    The caudal type homeo box transcription factors 1 (CDX1) and 2 (CDX2) are candidates for directing intestinal development, differentiation, and maintenance of the intestinal phenotype. CDX1 and CDX2 expression is widely present in the human intestinal and colonic mucosae, but not in the gastric mucosa, suggesting a possible role in the terminal differentiation of the intestine. Increased CDX2 expression is associated with chronic atrophic gastritis. Detectable expression of CDX2 precedes expression of CDX1 during the progression of intestinal metaplasia, thus expression of CDX2 may trigger the initiation and development of intestinal metaplasia. Markedly reduced or absent CDX2 expression was noted by immunohistochemistry in 13 of 15 (87 % ) large cell minimally differentiated carcinomas (LCMDCs), whereas only 1 of the 25 (4 %) differentiated adenocarcinomas (DACs) showed reduced CDX2 expression. Thus, a significant decrease in human CDX1 and/or CDX2 expression may be associated with colorectal tumorigenesis.
    分子量
    33520
    基因ID
    1045
    NCBI登录号
    NP_001256
    UniProt
    Q99626
    途径
    Peptide Hormone Metabolism, Stem Cell Maintenance
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