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USP4 抗体 (C-Term)

USP4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4269 unconjugated
产品编号 ABIN388883
发货至: 中国
  • 抗原 See all USP4 抗体
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    抗原表位
    • 15
    • 14
    • 10
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 903-933, C-Term
    适用
    • 55
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 54
    • 1
    • 1
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 24
    • 7
    • 7
    • 7
    • 5
    • 5
    • 1
    This USP4 antibody is un-conjugated
    应用范围
    • 41
    • 39
    • 36
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This USP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 903-933 amino acids from the C-terminal region of human USP4.
    克隆位点
    RB4269
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP4 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Laurell, Velázquez-Fernández, Lindsten, Juhlin, Enberg, Geli, Höög, Kjellman, Lundeberg, Hamberger, Larsson, Nilsson, Bäckdahl: "Transcriptional profiling enables molecular classification of adrenocortical tumours." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 141-52, (2009) (PubMed).

  • 抗原
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    别名
    USP4 (USP4 产品)
    别名
    UNP antibody, Unph antibody, F730026I20Rik antibody, Unp antibody, mKIAA4155 antibody, ubiquitin specific peptidase 4 antibody, ubiquitin specific peptidase 4 (proto-oncogene) antibody, USP4 antibody, Usp4 antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    分子量
    108565
    基因ID
    7375
    NCBI登录号
    NP_001238806, NP_003354, NP_955475
    UniProt
    Q13107
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