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UBE2D1 抗体 (C-Term)

UBE2D1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04139 unconjugated
产品编号 ABIN388843
发货至: 中国
  • 抗原 See all UBE2D1 抗体
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    抗原表位
    • 15
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 111-140, C-Term
    适用
    • 46
    • 21
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 3
    克隆类型
    • 42
    • 4
    多克隆
    标记
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2D1 antibody is un-conjugated
    应用范围
    • 35
    • 17
    • 13
    • 13
    • 11
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B, M, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This UBE2D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D1.
    克隆位点
    RB04139
    亚型
    Ig Fraction
    Top Product
    Discover our top product UBE2D1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    别名
    UBE2D1 (UBE2D1 产品)
    别名
    E2(17)KB1 antibody, SFT antibody, UBC4/5 antibody, UBCH5 antibody, UBCH5A antibody, ube2d1 antibody, wu:fc16h06 antibody, zgc:73096 antibody, e2(17)kb1 antibody, sft antibody, ubc4/5 antibody, ubch5 antibody, ubch5a antibody, ubiquitin conjugating enzyme E2 D1 antibody, ubiquitin-conjugating enzyme E2D 1 antibody, ubiquitin-conjugating enzyme E2D 1b antibody, ubiquitin conjugating enzyme E2 D1 S homeolog antibody, UBE2D1 antibody, Ube2d1 antibody, ube2d1b antibody, ube2d1.S antibody, ube2d1 antibody
    背景
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
    分子量
    16602
    基因ID
    7321
    NCBI登录号
    NP_003329
    UniProt
    P51668
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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