SMURF1 抗体 (C-Term)
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Quick Overview for SMURF1 抗体 (C-Term) (ABIN388829)
抗原
See all SMURF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 711-740, C-Term
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预测反应
- M, X
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SMURF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 711-740 amino acids from the C-terminal region of human SMURF1.
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亚型
- Ig Fraction
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anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 165-268) antibody
SMURF1 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 198-374) antibodySMURF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) antibodySMURF1 适用: 人, 小鼠 WB, IF, IHC (p), EIA, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 66-96), (N-Term) antibodySMURF1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB04101 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 1-731) antibodySMURF1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 66-96) antibodySMURF1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 165-269) antibodySMURF1 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (N-Term) antibodySMURF1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 165-268) antibodySMURF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 326-351), (Middle Region) antibodySMURF1 适用: 人, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity." in: The Journal of biological chemistry, Vol. 282, Issue 48, pp. 35259-68, (2007) (PubMed).
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- SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
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别名
- SMURF1
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背景
- SMURF1 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation and thereby their inactivation.
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分子量
- 86114
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基因ID
- 57154
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NCBI登录号
- NP_001186776, NP_065162, NP_851994
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UniProt
- Q9HCE7
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途径
- Regulation of Cell Size
抗原
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