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SMURF1 抗体 (C-Term)

SMURF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4103 unconjugated
产品编号 ABIN388829
发货至: 中国
  • 抗原 See all SMURF1 抗体
    SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 711-740, C-Term
    适用
    • 57
    • 23
    • 3
    宿主
    • 53
    • 4
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 22
    • 7
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMURF1 antibody is un-conjugated
    应用范围
    • 47
    • 39
    • 28
    • 10
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M, X
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SMURF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 711-740 amino acids from the C-terminal region of human SMURF1.
    克隆位点
    RB4103
    亚型
    Ig Fraction
    Top Product
    Discover our top product SMURF1 Primary Antibody
  • 应用备注
    WB: 1:500. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Schwamborn, Khazaei, Püschel: "The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity." in: The Journal of biological chemistry, Vol. 282, Issue 48, pp. 35259-68, (2007) (PubMed).

  • 抗原
    SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
    别名
    SMURF1 (SMURF1 产品)
    别名
    4930431E10Rik antibody, mKIAA1625 antibody, RGD1309707 antibody, SMAD specific E3 ubiquitin protein ligase 1 antibody, E3 ubiquitin-protein ligase SMURF1 antibody, SMAD specific E3 ubiquitin protein ligase 1 L homeolog antibody, SMURF1 antibody, LOC100540915 antibody, smurf1 antibody, Smurf1 antibody, smurf1.L antibody
    背景
    SMURF1 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation and thereby their inactivation.
    分子量
    86114
    基因ID
    57154
    NCBI登录号
    NP_001186776, NP_065162, NP_851994
    UniProt
    Q9HCE7
    途径
    Regulation of Cell Size
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