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SOX2 抗体 (N-Term)

SOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated
产品编号 ABIN388797
发货至: 中国
  • 抗原 See all SOX2 抗体
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    抗原表位
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 12
    • 10
    • 10
    • 9
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 89-119, N-Term
    适用
    • 203
    • 96
    • 69
    • 21
    • 13
    • 11
    • 11
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    宿主
    • 165
    • 42
    • 2
    克隆类型
    • 162
    • 47
    多克隆
    标记
    • 103
    • 16
    • 15
    • 10
    • 10
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOX2 antibody is un-conjugated
    应用范围
    • 165
    • 109
    • 46
    • 46
    • 44
    • 40
    • 40
    • 28
    • 26
    • 25
    • 18
    • 15
    • 12
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Zf, X, C, M, Sh
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-119 amino acids from the N-terminal region of human SOX2.
    克隆位点
    RB14026
    亚型
    Ig Fraction
    Top Product
    Discover our top product SOX2 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Schouten, Fratantoni, Hubens, Piersma, Pham, Bielefeld, Voskuyl, Lucassen, Jimenez, Fitzsimons: "MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells." in: Scientific reports, Vol. 5, pp. 12448, (2015) (PubMed).

    Su, Qi: "Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4545-61, (2013) (PubMed).

  • 抗原
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    别名
    SOX2 (SOX2 产品)
    别名
    ANOP3 antibody, MCOPS3 antibody, RGD1565646 antibody, Sox-2 antibody, lcc antibody, ysb antibody, cb236 antibody, wu:fb83g04 antibody, wu:fc14d07 antibody, zgc:65860 antibody, zgc:77389 antibody, SRY-box2 antibody, Xsox-2 antibody, anop3 antibody, mcops3 antibody, sox-2 antibody, SRY-box 2 antibody, SRY box 2 antibody, SRY (sex determining region Y)-box 2 antibody, SRY-box 2 S homeolog antibody, SOX2 antibody, Sox2 antibody, sox2 antibody, sox2.S antibody
    背景
    The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
    分子量
    34310
    基因ID
    6657
    NCBI登录号
    NP_003097
    UniProt
    P48431
    途径
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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