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- 抗原 See all NCAPH2 抗体
- NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))
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抗原表位
- AA 198-227, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCAPH2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This NCAPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the N-terminal region of human NCAPH2.
- 克隆位点
- RB9657
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NCAPH2 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell death." in: Cell death and differentiation, Vol. 18, Issue 6, pp. 996-1004, (2011) (PubMed).
: "Detection of condensin I and II in maturing pig oocytes." in: Reproduction, fertility, and development, Vol. 22, Issue 4, pp. 644-52, (2010) (PubMed).
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Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell death." in: Cell death and differentiation, Vol. 18, Issue 6, pp. 996-1004, (2011) (PubMed).
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- 抗原
- NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))
- 别名
- NCAPH2 (NCAPH2 产品)
- 别名
- MGC81656 antibody, CAPH2 antibody, si:dkey-202b22.2 antibody, non-SMC condensin II complex subunit H2 antibody, non-SMC condensin II complex subunit H2 L homeolog antibody, non-SMC condensin II complex, subunit H2 antibody, NCAPH2 antibody, ncaph2.L antibody, ncaph2 antibody, Ncaph2 antibody
- 背景
- Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.
- 分子量
- 68227
- 基因ID
- 29781
- NCBI登录号
- NP_001171940, NP_055366, NP_689512
- UniProt
- Q6IBW4
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