MAP1LC3A 抗体
(9 references)-
- 抗原 See all MAP1LC3A 抗体
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAP1LC3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This LC3 antibody is generated from rabbits immunized with full-length recombinant human LC3 (APG8a).
- 克隆位点
- RB7993
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MAP1LC3A Primary Antibody
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anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 89-120), (cleaved) antibody
MAP1LC3A 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal RB38908 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibodyMAP1LC3A 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B10D8 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibodyMAP1LC3A 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B10D8 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term) antibodyMAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7481 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibodyMAP1LC3A 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-120) antibodyMAP1LC3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibodyMAP1LC3A 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibodyMAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 166AT1234 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term), (pSer12) antibodyMAP1LC3A 适用: 人 WB, DB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibodyMAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 5G10 unconjugated
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- 应用备注
- IF: 1:200. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients." in: PLoS ONE, Vol. 11, Issue 7, pp. e0157404, (2017) (PubMed).
: "Thrombin preferentially induces autophagy in glia cells in the rat central nervous system." in: Neuroscience letters, Vol. 630, pp. 53-58, (2017) (PubMed).
: "A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer." in: Cancer letters, Vol. 400, pp. 79-88, (2017) (PubMed).
: "The effect of RNAi silencing of p62 using an osmotic polysorbitol transporter on autophagy and tumorigenesis in lungs of K-rasLA1 mice." in: Biomaterials, Vol. 35, Issue 5, pp. 1584-96, (2013) (PubMed).
: "Involvement of melatonin in autophagy-mediated mouse hepatoma H22 cell survival." in: International immunopharmacology, Vol. 12, Issue 2, pp. 394-401, (2012) (PubMed).
: "Induction of autophagy is essential for monocyte-macrophage differentiation." in: Blood, Vol. 119, Issue 12, pp. 2895-905, (2012) (PubMed).
: "Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin." in: The Journal of pharmacology and experimental therapeutics, Vol. 337, Issue 1, pp. 65-74, (2011) (PubMed).
: "Inhibition of histone deacetylase causes emphysema." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 300, Issue 3, pp. L402-13, (2011) (PubMed).
: "RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats." in: Acta pharmacologica Sinica, Vol. 30, Issue 7, pp. 919-27, (2009) (PubMed).
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: "Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients." in: PLoS ONE, Vol. 11, Issue 7, pp. e0157404, (2017) (PubMed).
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- 抗原
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
- 别名
- LC3 (MAP1LC3A 产品)
- 别名
- ATG8E antibody, LC3 antibody, LC3A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, 1010001H21Rik antibody, 4922501H04Rik antibody, LC3a antibody, MGC69006 antibody, zgc:77094 antibody, MGC89867 antibody, MAP1LC3A antibody, map1lc3a antibody, microtubule associated protein 1 light chain 3 alpha antibody, microtubule-associated protein 1 light chain 3 alpha antibody, microtubule associated protein 1 light chain 3 alpha S homeolog antibody, MAP1LC3A antibody, Map1lc3a antibody, map1lc3a.S antibody, map1lc3a antibody
- 背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3a is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
- 基因ID
- 84557
- NCBI登录号
- NP_115903, NP_852610
- UniProt
- Q9H492, Q9GZQ8
- 途径
- Autophagy
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