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SUMO2 抗体 (C-Term)

SUMO2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2761 unconjugated
产品编号 ABIN388085
发货至: 中国
  • 抗原 See all SUMO2 抗体
    SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
    抗原表位
    • 30
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 63-93, C-Term
    适用
    • 105
    • 35
    • 29
    • 8
    • 2
    • 1
    • 1
    • 1
    宿主
    • 89
    • 24
    • 1
    克隆类型
    • 90
    • 25
    多克隆
    标记
    • 60
    • 12
    • 9
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SUMO2 antibody is un-conjugated
    应用范围
    • 75
    • 65
    • 43
    • 22
    • 15
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    X, Zf, B, C, Ha, Pr, M, Pig, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the C-terminal region of human SUMO2.
    克隆位点
    RB2761
    亚型
    Ig Fraction
    Top Product
    Discover our top product SUMO2 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Ito, Nakamura, Mori, Miki, Tanji, Wakabayashi: "Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 5, pp. 441-447, (2017) (PubMed).

    Mori, Tanji, Odagiri, Hattori, Hoshikawa, Kono, Yasui, Yokoi, Hasegawa, Kamitani, Yoshida, Wakabayashi: "Ubiquitin-related proteins in neuronal and glial intranuclear inclusions in intranuclear inclusion body disease." in: Pathology international, Vol. 62, Issue 6, pp. 407-11, (2012) (PubMed).

    Mori, Miki, Tanji, Ogura, Yagihashi, Jensen, Wakabayashi: "Incipient intranuclear inclusion body disease in a 78-year-old woman." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 31, Issue 2, pp. 188-93, (2011) (PubMed).

    Janer, Werner, Takahashi-Fujigasaki, Daret, Fujigasaki, Takada, Duyckaerts, Brice, Dejean, Sittler: "SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7." in: Human molecular genetics, Vol. 19, Issue 1, pp. 181-95, (2009) (PubMed).

    Zhang, Sarge: "Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies." in: The Journal of cell biology, Vol. 182, Issue 1, pp. 35-9, (2008) (PubMed).

  • 抗原
    SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
    别名
    SUMO2 (SUMO2 产品)
    别名
    HSMT3 antibody, SMT3B antibody, SMT3H2 antibody, SUMO3 antibody, Smt3A antibody, SMT3A antibody, SMT3H1 antibody, SUMO-3 antibody, Smt3B antibody, Smt3h2 antibody, sumo2 antibody, zgc:92241 antibody, SUMO2 antibody, SUMO-2 antibody, Smt3b antibody, hsmt3 antibody, smt3b antibody, smt3h2 antibody, sumo-2 antibody, PSMT3 antibody, ATSUMO2 antibody, MCO15.11 antibody, MCO15_11 antibody, SMALL UBIQUITIN-LIKE MODIFIER 2 antibody, SUM2 antibody, SUMO 2 antibody, small ubiquitin-like modifier 2 antibody, small ubiquitin-like modifier 2 antibody, small ubiquitin-like modifier 3 antibody, small ubiquitin-like modifier 2b antibody, small ubiquitin-related modifier 2 antibody, small ubiquitin-like modifier 2 S homeolog antibody, small ubiquitin-like modifier 2 L homeolog antibody, SUMO2 antibody, SUMO3 antibody, Sumo2 antibody, sumo2b antibody, LOC714892 antibody, sumo2.S antibody, sumo2.L antibody
    背景
    SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
    分子量
    10871
    基因ID
    6613
    NCBI登录号
    NP_001005849, NP_008868
    UniProt
    P61956
    途径
    Methionine Biosynthetic Process
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