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SENP6 抗体 (C-Term)

SENP6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0664 unconjugated
产品编号 ABIN388052
发货至: 中国
  • 抗原 See all SENP6 抗体
    SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
    抗原表位
    • 17
    • 8
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1081-1112, C-Term
    适用
    • 52
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 48
    • 2
    • 2
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 22
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SENP6 antibody is un-conjugated
    应用范围
    • 37
    • 31
    • 24
    • 8
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SENP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1081-1112 amino acids from the C-terminal region of human SENP6.
    克隆位点
    RB0664
    亚型
    Ig Fraction
    Top Product
    Discover our top product SENP6 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Lee, Lee, Park, Kang, Yoo, Ka, Oh, Jeon, Chung: "SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage." in: The EMBO journal, Vol. 31, Issue 23, pp. 4441-52, (2012) (PubMed).

    Jones, Fusi, Higham, Abdel-Hafiz, Horwitz, Lam, Brosens: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).

    Choi, Chung, Rho, Lee, Lee, Choi, Seol, Baek, Bang, Chung: "Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30669-77, (2006) (PubMed).

  • 抗原
    SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
    别名
    SENP6 (SENP6 产品)
    别名
    SSP1 antibody, SUSP1 antibody, 2810017C20Rik antibody, E130319N12Rik antibody, Susp1 antibody, mKIAA0797 antibody, fc83h02 antibody, im:7148342 antibody, wu:fc83h02 antibody, zgc:171230 antibody, SUMO1/sentrin specific peptidase 6 antibody, SUMO/sentrin specific peptidase 6 antibody, SUMO1/sentrin specific peptidase 6a antibody, SENP6 antibody, Senp6 antibody, senp6a antibody
    背景
    SENP6 (SUSP1) is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. This protein does not seem to be involved in the processing of full-length SUMO proteins to their mature conjugatable forms. SENP6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. It may act preferentially on substrates containing 3 or more SUMO2 or SUMO3 moieties.
    分子量
    126146
    基因ID
    26054
    NCBI登录号
    NP_001093879, NP_056386
    UniProt
    Q9GZR1
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