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HDAC11 抗体 (C-Term)

HDAC11 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2589 unconjugated
产品编号 ABIN387965
发货至: 中国
  • 抗原 See all HDAC11 抗体
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 313-345, C-Term
    适用
    • 49
    • 43
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 59
    • 5
    克隆类型
    • 60
    • 4
    多克隆
    标记
    • 37
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HDAC11 antibody is un-conjugated
    应用范围
    • 54
    • 33
    • 22
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-345 amino acids from the C-terminal region of human HDAC11.
    克隆位点
    RB2589
    亚型
    Ig Fraction
    Top Product
    Discover our top product HDAC11 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Joshi, Greco, Guise, Luo, Yu, Nesvizhskii, Cristea: "The functional interactome landscape of the human histone deacetylase family." in: Molecular systems biology, Vol. 9, pp. 672, (2013) (PubMed).

    Keedy, Archin, Gates, Espeseth, Hazuda, Margolis: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." in: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).

  • 抗原
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    别名
    HDAC11 (HDAC11 产品)
    别名
    CG31119 antibody, DHDACX antibody, Dmel\\CG31119 antibody, HDAC11 antibody, HDACX antibody, dHDAC11 antibody, dmHDA403 antibody, zgc:91942 antibody, HD11 antibody, histone deacetylase 11 antibody, Histone deacetylase 11 antibody, hypothetical protein antibody, HDAC11 antibody, hdac11 antibody, CpipJ_CPIJ001619 antibody, Bm1_15905 antibody, LOAG_18214 antibody, Hdac11 antibody
    背景
    HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
    分子量
    39183
    基因ID
    79885
    NCBI登录号
    NP_001129513, NP_079103
    UniProt
    Q96DB2
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